5-Cog 2.0: Improving Dementia Detection in Primary Care
This study, called 5-Cog 2.0, is looking at ways to better identify cognitive impairment (problems with thinking, memory, and judgment) in older adults. It's testing two approaches: the 5-Cog Paradigm, which uses a quick cognitive assessment (5-Cog battery) along with a tool to help doctors make decisions, and Enhanced Usual Care, where doctors receive screening results. Both approaches start with a screening for cognitive concerns before your primary care appointment. The study aims to see if these methods lead to more new diagnoses of cognitive impairment within 90 days. You might be able to join if you are 65 or older, have cognitive concerns, speak English or Spanish, and can see and hear well enough for assessments. The study is currently unclear on its recruitment status and plans to enroll 6600 participants.
- Study design
- This is an interventional study, meaning participants will receive a specific intervention. It plans to enroll 6600 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study measures new cognitive impairment diagnoses in the 90-day period following presentation of cognitive concern to the primary care physician.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
5-Cog 2.0: A Pragmatic Clinical Trial
At a glance
Conditions
NCT05515224
Where you'd take part
This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Albert Einstein College of Medicine
The Bronx, New Yorkstudy coordinator listed
Recruiting
Indiana University
Bloomington, Indianano site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Joe Verghese, MD · PRINCIPAL_INVESTIGATOR · Stony Brook University
- Malaz Boustani, MD, MPH · PRINCIPAL_INVESTIGATOR · Indiana University
- Erica Weiss, PhD · PRINCIPAL_INVESTIGATOR · Albert Einstein College of Medicie
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- New cognitive impairment diagnoses in the 90-day period following presentation of cognitive concern to the primary care physician (PCP).Up to 90 days
The clinical effectiveness of the 5-Cog paradigm on new cognitive impairment detection will be examined by comparing the proportion of 'new Mild Cognitive Impairment (MCI) and dementia diagnoses' over 90-days in the 5-cog paradigm and the enhanced usual care group using generalized linear mixed effects models. For patients with a previous diagnosis of MCI in the electronic medical record, only a new diagnosis of dementia will be considered as an incident outcome.