This study is looking at how transcutaneous Vagal Nerve Stimulation (tcVNS) affects symptoms of Post-Traumatic Stress Disorder (PTSD) in Veterans. tcVNS is a device that delivers gentle electrical pulses to a nerve in your neck. You would receive either the active tcVNS device or a sham device (which looks and feels similar but doesn't deliver active treatment). Researchers will measure changes in your PTSD symptoms and brain activity over three months. To join, you must be a Veteran between 18 and 75 years old with a PTSD diagnosis. You cannot have a history of moderate or severe traumatic brain injury, certain neurological conditions, or substance abuse. The study's current status is unclear.

Study design

This interventional study plans to enroll 80 participants who will be randomly assigned to receive either active tcVNS or sham stimulation. It is a blinded study, meaning neither you nor the researchers will know which treatment you are receiving.

What's involved

You would undergo brain imaging and physiological tests before and after three months of using the tcVNS or sham device twice daily at home. You will also be exposed to stressful traumatic scripts during some assessments.

Compensation

Not stated in the trial record.

Follow-up

Your PTSD symptoms will be measured from the start of the study up to three months later.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.