Antibiotics Before Bladder Botox Injections
This study is looking at whether giving antibiotics (Nitrofurantoin) before bladder Botox injections is truly necessary. The goal is to see if not giving antibiotics is just as safe as giving them, which could help reduce antibiotic resistance. You could be eligible if you are an adult woman (18 or older) who is scheduled to receive bladder Botox. You cannot participate if you are pregnant, breastfeeding, or have certain health conditions that prevent you from getting Botox. Participants will be randomly assigned to either receive oral antibiotics for a few days around their Botox procedure or not receive them. The main thing the researchers will be looking for is how many people get urinary tract infections (UTIs) two weeks after the procedure. The study's status is currently unclear, and it plans to enroll 140 participants.
- Study design
- This is a single-center, randomized-controlled trial involving 140 participants. You will be randomly assigned to either receive antibiotics or not.
- What's involved
- You will have a urine culture about 14 days before the procedure. You will return for a follow-up appointment about 2 weeks after treatment and receive a phone call at 6 weeks for another follow-up.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for urinary tract infection symptoms at 2 weeks and again at 6 weeks after treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Use of Prophylactic Antibiotics Prior to OnabotulinumtoxinA
At a glance
Conditions
NCT05519072
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Atlantic Health
Morristown, New Jerseystudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Carolyn Botros, DO · PRINCIPAL_INVESTIGATOR · Atlantic Health System
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- Urinary tract infections2 weeks post-procedure
Number of participants with urinary tract infections