Reducing Blood Pressure in Mid-life Adult Binge Drinkers

This study is looking at ways to lower blood pressure in adults aged 50-64 who binge drink. Researchers want to see if high-intensity interval training (a type of exercise) and an alcohol abstinence intervention (stopping alcohol use) can help. The study will compare binge drinkers to those who don't drink or drink moderately. The main goal is to see if the exercise training is practical to do throughout the study, which lasts about three months. You could be eligible if you are a man or postmenopausal woman aged 50-64, can speak English, and do not have certain health conditions like diabetes or heart disease. The current recruitment status is unclear.

Study design
This interventional study plans to enroll 55 participants. It has two phases, with only binge drinkers entering the second phase where they will be randomly assigned to an exercise or non-exercise group.
What's involved
If you are a binge drinker, you would be asked to abstain from alcohol for 8 weeks with provided education and consultations. If in the exercise group, you would perform supervised high-intensity interval training 3 times a week for 8 weeks, with each session lasting 40 minutes.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, feasibility of high-intensity interval training, is measured throughout the study participation (~3 months).

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NCT05522075

Reducing Blood Pressure in Mid-life Adult Binge Drinkers

Recruiting
NAAges 50–64InterventionalPrevention
The University of Texas at Arlington
~55 participants
Updated 2026-06-01 on ClinicalTrials.gov
What's tested:Exercise TrainingAlcohol Abstinence Intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility of high-intensity interval training
Measured over Through out the study participation (~3 months)
Alcohol Drinking
Binge Drinking
Blood Pressure
Alcohol Abstinence
Aging
Lifestyle Factors
Vasodilation
Behavioral Problem
1 sites across 1 states
Texas1
  • Chueh-Lung Hwang, PhD · PRINCIPAL_INVESTIGATOR · University of Texas at Arlington

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Eligibility criteria

Inclusion

Men and women (50-64 years of age) who do not drink alcohol, who drink at moderate levels, or who binge drink
Female subjects will be postmenopausal (i.e., cessation of menses for ≥1 yr).
Subjects who can speak and understand English.

Exclusion

a history of diabetes, cardiovascular disease, liver, or renal disease
current or history of smoking and illicit drug use
blood pressure ≥160/100 mm Hg
other known traditional cardiovascular disease risks: obesity (BMI≥35 kg/m2), or hyperlipidemia (total cholesterol\>230 mg/dl and/or LDL cholesterol\>160 mg/dl)
active infection (in the past 2 months)
a history of seizures, cancer, or inflammatory disease (i.e., gout or rheumatoid)
unstable body weight (\>5% change during the past 6 months)
regular aerobic exercise training (i.e., they engage in 30 min of structured aerobic exercise at least 3 times per week)
current use of hormone replacement therapy (i.e., estrogen, progesterone, and testosterone)
  • Feasibility of high-intensity interval trainingThrough out the study participation (~3 months)

    Recruitment capacity (e.g., how many subjects respond and enter to the study or reasons of refusal), resulting subject characteristics, the number of exercise session attended, and the number of dropouts