Amblyopia Treatment Study: Video Games and Perceptual Learning
This study is exploring new ways to treat amblyopia (sometimes called "lazy eye"), a condition that affects how well you see. We are testing two approaches: Video Game Vision Training, which uses video games to improve vision, and Perceptual Learning, which involves practicing visual tasks. We are comparing these new methods to Occlusion Therapy, a standard amblyopia treatment. We want to see how these treatments change your visual sharpness (visual acuity) and depth perception (stereoacuity) over 9 months. Adults and children with normal vision or amblyopia can join, as long as your amblyopia causes a certain difference in vision between your eyes. You cannot join if you have other eye conditions or nystagmus (involuntary eye movements). The study is currently unclear on its recruitment status.
- Study design
- This interventional study plans to enroll 180 participants to compare different behavioral treatments for amblyopia.
- What's involved
- Participants will practice a visual discrimination task (perceptual learning) or play video games with their amblyopic eye for a period of time. Visual functions will be monitored during treatment.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your visual acuity and stereoacuity will be measured before and after the intervention, at 9 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video Games
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Roger W Li, OD, PhD · PRINCIPAL_INVESTIGATOR · Nova Southeastern University College of Optometry
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in visual acuity before and after the intervention9 months
"Visual acuity", the gold standard for vision testing, will be measured. Participants will be asked to read letters on a LogMAR letter chart. The smallest letters that can be read correspond to visual acuity (e.g., Snellen acuity of 20/20, letter-stroke width = 1 minute of arc).
- Change in stereoacuity before and after the intervention9 months
"Stereoacuity" will be measured psychophysically using a new stereoacuity function test (1.25, 2.5, 5, 10, 15, \& 20 cycles per degree) developed in our previous studies (Li et al 2016). A custom-built 4-mirror haploscope will be used to present a stereogram to each eye. Stereoacuity is the smallest stereo disparity that can be seen in binocular vision (in the unit of seconds of arc, arcsec). The conventional stereoacuity tests (including Randot Stereoacuity Test, Stereofly Test \& Preschool Stereo Test) will also be used to measure stereoacuity. Participants will be asked to wear a pair of 3D glasses and to identify the target 3D pictures at various 3D levels. The smallest 3D disparities that can be seen correspond to stereoacuity (e.g. normal range of stereoacuity: 50 seconds of arc or better).