Noninvasive Brain Stimulation for Reading Disability

This study is looking at new ways to help adults with reading difficulties. It's testing non-invasive brain stimulation (tACS) to see if it can improve reading comprehension. There are three groups: one gets a sham (inactive) device, one gets real stimulation to the left angular gyrus (RLN), and another gets stimulation to both the left dorsolateral prefrontal cortex and left angular gyrus (RLN and CCN). Researchers will measure changes in reading comprehension on standardized tests over 12 months. You might be able to join if you are right-handed, a native English speaker, between 18 and 40 years old, and have a reading disability. The study is currently recruiting 100 participants, but its status is unclear.

Study design
This is an interventional study planning to enroll 100 participants. It compares three different approaches to non-invasive brain stimulation.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your reading comprehension will be measured from the start of the study up to 12 months later.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05523505

Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults

Recruiting
NAAges 18–40InterventionalTreatment
Vanderbilt University
~100 participants
Updated 2025-08-01 on ClinicalTrials.gov
What's tested:Sham interventionRLN real non-invasive brain stimulation interventionRLN and CCN real non-invasive brain stimulation intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in reading comprehension ability on standardized test measure
Measured over Baseline to 12 months
+1 more outcome measured
Reading Disability
1 sites across 1 states
Tennessee1
  • Katherine S. Aboud, PhD · PRINCIPAL_INVESTIGATOR · Vanderbilt University

Opens a ready-to-send draft in your own email app — review before sending.

  • Change in reading comprehension ability on standardized test measureBaseline to 12 months

    Stimulation induced change in reading comprehension ability measured by Gates MacGinitie Reading Test: * Reading Comprehension Subtest (Adult Reader; AR): Participants have 35 minutes to read passages and answer 48 comprehension questions about what they read. * Percentile Ranks based on the scores of entering community college students * Primary outcome measure is the change in percentile ranks

  • Performance in reading comprehension ability on test measure during stimulation sessionBaseline to 12 months

    Stimulation induced performance in reading comprehension ability measured by free recall of information learned while reading during stimulation session. * Subject asks to recall content from 100 total sentences * Primary outcome measure is the number correct out of total (# recalled / total) compared across groups (real stimulation subgroups and sham).