Studying Food Intake Regulation Using Functional MRI
This study is looking for healthy volunteers aged 21 to 50 with a BMI between 18-25 kg/m² to understand how your gut and brain respond to different types of food and how this affects your appetite. You'll undergo Functional Magnetic Resonance Imaging (fMRI) scans at different times. Researchers will also use an Intragastric Balloon (a balloon placed in your stomach and inflated), and you'll eat two types of meals: an Elemental Meal (a tasteless meal) and a Hedonic Meal (a meal of your choice). The main goal is to see how blood flow in a part of your brain called the hypothalamus changes after these interventions, measured after one month. The study is currently recruiting 15 participants, but its status is unclear.
- Study design
- This interventional study plans to enroll 15 healthy participants. It investigates how the brain and gut respond to different food stimuli.
- What's involved
- You will have multiple visits where you'll undergo MRI scans, have an Intragastric Balloon placed, and eat specific meals until you feel full.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, measuring brain blood flow, is assessed at one month.
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Studying the Hedonic and Homeostatic Regulation of Food Intake Using Functional MRI
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Andres Acosta, MD, PhD · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Difference in Cerebral Blood Flow related to hypothalamus1 month
The mean difference in cerebral blood flow (CBF) at fullness (satiation) and return to hunger (satiety) to the hypothalamic area.