Cardiac Rehabilitation for Long COVID-19

This study is testing if a program called cardiac rehabilitation can improve how well people with Long COVID can exercise and how their heart rate responds during activity. Cardiac rehabilitation involves personalized exercise plans based on your heart's performance during a baseline CPET (cardiopulmonary exercise test). You might be able to join if you are 18 or older, have a confirmed history of COVID-19, and have ongoing symptoms for at least three months that weren't present before your infection. The study is looking to see if this rehabilitation improves your exercise capacity (how much oxygen your body can use during exercise) and your heart rate response after 12 weeks. The current status of this study is unclear.

Study design
This is a single-center study with 20 participants. It uses a pre-post design, meaning measurements are taken before and after the intervention.
What's involved
You will undergo baseline measurements, participate in 12 weeks of cardiac rehabilitation, and then have follow-up measurements. You will also be asked to co-enroll in another observational study.
Compensation
Not stated in the trial record.
Follow-up
Follow-up measurements will be taken after 12 weeks of cardiac rehabilitation.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05530317

CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVID-19

Terminated
NAAges 18+InterventionalTreatment
University of California, San Francisco
~13 participants
Updated 2026-08-13 on ClinicalTrials.gov
What's tested:Cardiac Rehabilitation

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in adjusted heart rate reserve
Measured over Baseline and 12 weeks
+1 more outcome measured
Long COVID
COVID-19

NCT05530317

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of California, San Francisco

    San Francisco, Californiano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Matthew S Durstenfeld, MD MAS · PRINCIPAL_INVESTIGATOR · University of California, San Francisco

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Change in adjusted heart rate reserveBaseline and 12 weeks

    Adjusted heart rate reserve (peak HR-rest HR)/(220-age-rest HR) achieved during symptom-limited maximal cardiopulmonary testing performed with cycle ergometer

  • Change in Peak VO2 (ml/kg/min)Baseline and 12 weeks

    Peak VO2 measured with maximal symptom limited cardiopulmonary exercise testing