Prophylactic Radiotherapy for Minimally Symptomatic Spinal Disease

This study is looking at whether early radiation therapy (Prophylactic Radiotherapy) can help prevent problems in people with cancer that has spread to their spine (Spine Metastases). You might be able to join if you have a solid tumor and cancer that has spread to more than five places, including your spine, and your spinal pain is mild or you have no pain. The study will compare patients who receive radiation therapy to those who receive standard cancer treatments (Standard of care systemic therapy). Researchers want to see how many people have skeletal-related events (like fractures or needing surgery) within one year. The current status of this study is unclear.

Study design
This interventional study plans to enroll 74 participants. It is not specified if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for one year to measure the number of skeletal-related events.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05534321

Prophylactic Radiotherapy of MInimally Symptomatic Spinal Disease

Recruiting
PHASE1Ages 18+InterventionalSupportive care
Baptist Health South Florida
~74 participants
Updated 2026-02-17 on ClinicalTrials.gov
What's tested:Prophylactic RadiotherapyStandard of care systemic therapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of patients who have skeletal-related events (SREs)
Measured over 1 year
Spine Metastases

NCT05534321

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Miami Cancer Institute at Baptist Health South Florida

    Miami, Floridastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Rupesh R Kotecha, MD · PRINCIPAL_INVESTIGATOR · Miami Cancer Institute

Opens a ready-to-send draft in your own email app — review before sending.

  • Number of patients who have skeletal-related events (SREs)1 year

    Number of skeletal related events (SREs), which will be defined as pathological fractures, spinal cord compression, or interventions (palliative RT, interventional procedures, or spine surgery)