Music for Cardiopulmonary Exercise in Heart Failure

This study is looking at whether listening to upbeat music through headphones can improve how well people with heart failure exercise. Researchers will compare heart failure patients who listen to music during a Cardiopulmonary Exercise (CPX) test with those who don't. The study aims to see if music changes how much oxygen your body uses (VO2), how much carbon dioxide it produces (VCO2), and your respiratory exchange ratio (RER) during exercise. You might be able to join if you are an adult (18 or older), can give consent, and speak English. You cannot join if you have severe hearing problems or cannot exercise. The study is hoping to enroll 40 participants.

Study design
This is an interventional study with 40 planned participants. You would be randomly assigned to either listen to music or not during an exercise test.
What's involved
You would undergo Cardiopulmonary Exercise (CPX) testing. If in the music group, you would listen to music via headphones during this test.
Compensation
Not stated in the trial record.
Follow-up
Measurements for the primary endpoints are taken at 15 minutes during the exercise test.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05537467

Effect of Music on Cardiopulmonary Exercise Capacity in Heart Failure Patients

Recruiting
NAAges 18+InterventionalTreatment
Maya Ignaszewski
~40 participants
Updated 2026-01-08 on ClinicalTrials.gov
What's tested:Music

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Difference in O2 consumption (VO2) [L/min]
Measured over 15 minutes (at baseline 8 breaths, Anaerobic Threshold 8 breaths, Peak 8 Breaths)
+6 more outcomes measured
Heart Failure

NCT05537467

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Kentucky

    Lexington, Kentuckystudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Maya T Ignaszewski, MD · PRINCIPAL_INVESTIGATOR · University of Kentucky

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Eligibility criteria

Inclusion

Adults (age \>18 years)
Able to consent
English speaking

Exclusion

Severe hearing deficiency
Unable to exercise.
  • Difference in O2 consumption (VO2) [L/min]15 minutes (at baseline 8 breaths, Anaerobic Threshold 8 breaths, Peak 8 Breaths)

    Assess above performance parameters in CPX and compare between Music and Non-Music arm.

  • Difference in CO2 production (VCO2) [L/min]15 minutes (at baseline 8 breaths, Anaerobic Threshold 8 breaths, Peak 8 Breaths)

    Assess above performance parameters in CPX and compare between Music and Non-Music arm.

  • Difference in respiratory exchange ratio (RER)15 minutes (at baseline 8 breaths, Anaerobic Threshold 8 breaths, Peak 8 Breaths)

    Assess above performance parameters in CPX and compare between Music and Non-Music arm.

  • Difference in Minute Ventilation (VE) [L/min]15 minutes (at baseline 8 breaths, Anaerobic Threshold 8 breaths, Peak 8 Breaths)

    Assess above performance parameters in CPX and compare between Music and Non-Music arm

  • Difference in Ventilatory Threshold (VT) [L]15 minutes (at baseline 8 breaths, Anaerobic Threshold 8 breaths, Peak 8 Breaths)

    Assess above performance parameters in CPX and compare between Music and Non-Music arm

  • Difference in respiratory rate (RR) [Breaths per minute]15 minutes (at baseline 8 breaths, Anaerobic Threshold 8 breaths, Peak 8 Breaths)

    Assess above performance parameters in CPX and compare between Music and Non-Music arm

  • Difference in Ventilatory Equivalent of CO2 (VE/VCO2)15 minutes (at baseline 8 breaths, Anaerobic Threshold 8 breaths, Peak 8 Breaths)

    Assess above performance parameters in CPX and compare between Music and Non-Music arm