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NCT05554692

Peripheral and Central Influences on Auditory Temporal Processing & Speech Perception in Older Cochlear Implantees

Enrolling by Invitation
NAAges 18–85InterventionalBasic science
University of Maryland, College Park
~300 participants
Updated 2025-03-25 on ClinicalTrials.gov
What's tested:Diagnostic tests of cochlear implant functionDiagnostic tests of auditory function

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Perceptual forward-masking recovery
Measured over Post-treatment - after at least 1 year use of a cochlear implant if CI user. No required time frame for NH comparison listeners. This measure will be collected once within a 6-month time period for each participant.
+5 more outcomes measured

Conditions

Hearing Loss
Cochlear Hearing Loss
Hearing Loss, Sensorineural
Aging

Explore related trials

Hearing LossSensorineural Hearing LossSensory Hearing Loss

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Matthew J. Goupell, PhD · PRINCIPAL_INVESTIGATOR · University of Maryland, College Park
  • Samira B. Anderson, PhD · STUDY_DIRECTOR · University of Maryland, College Park
  • Sandra Gordon-Salant, PhD · STUDY_DIRECTOR · University of Maryland, College Park

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

cochlear implant in one or both ears
post-lingual onset of deafness
1+ years cochlear implant experience
use of Cochlear-brand implants
implanted after 2004
audiometrically normal hearing, near-normal hearing, or mild/moderate hearing loss.

Exclusion

use of non-Cochlear-brand cochlear implants
no use of oral language
pregnant women are not eligible for the imaging portion of the study.
residual acoustic hearing with unaided thresholds \<90 dB HL at more than two standard audiometric frequencies
other known disability or neurological disorder
severe hearing loss
history of neurological disorders
history of middle-ear disorders

What this trial measures

  • Perceptual forward-masking recoveryPost-treatment - after at least 1 year use of a cochlear implant if CI user. No required time frame for NH comparison listeners. This measure will be collected once within a 6-month time period for each participant.

    Basic measurement of temporal processing - A masker stimulus encountered before a probe/target stimulus can affect the perception of the probe stimulus to a greater/lesser degree depending on their separation in time and their absolute and relative levels. Percent correct discrimination as a function of time separation and level manipulations, as measured from a behavioral response, will be reported.

  • Perceptual gap detection thresholdsPost-treatment - after at least 1 year use of a cochlear implant if CI user. No required time frame for NH comparison listeners. This measure will be collected once within a 6-month time period for each participant.

    Basic behavioral measurement of temporal processing - The ability to detect a silent gap within a stimulus typically varies depending on frequency and level characteristics of the stimulus in which the gap is embedded and also with the hearing history and age of the listener. Gap detection threshold is the shortest gap duration that can be reliably detected under a given set of conditions and is typically reported in milliseconds.

  • Perceptual duration discrimination thresholdsPost-treatment - after at least 1 year use of a cochlear implant if CI user. No required time frame for NH comparison listeners. This measure will be collected once within a 6-month time period for each participant.

    Basic measurement of temporal processing - Perceptual duration discrimination thresholds summarize a listener's ability to tell apart stimuli that differ in temporal extent. Percent correct discrimination as a function of duration difference, overall stimulus duration, and level manipulations, as measured from a behavioral response, will be reported.

  • Perceptual amplitude discrimination thresholdsPost-treatment - after at least 1 year use of a cochlear implant if CI user. No required time frame for NH comparison listeners. This measure will be collected once within a 6-month time period for each participant.

    Basic measurement of auditory processing - Perceptual amplitude discrimination thresholds summarize a listener's ability to tell apart stimuli that differ in level. Percent correct discrimination as a function of level difference size and average level, as measured from a behavioral response, will be reported.

  • Speech perceptionPost-treatment - after at least 1 year use of a cochlear implant if CI user. No required time frame for NH comparison listeners. This measure will be collected once within a 6-month time period for each participant.

    Word discrimination, consonant, vowel, and sentence perception tests. The ability to discriminate between and identify recorded words, phonemic contrasts, and sentences will be assessed behaviorally. Results are reported in terms of percent correct words or phonemes.

  • Amplitude modulation detection performancePost-treatment - after at least 1 year use of a cochlear implant if CI user. No required time frame for NH comparison listeners. This measure will be collected once within a 6-month time period for each participant.

    Measure of ability to perceive amplitude modulation using modulation depth thresholds. Amplitude modulation detection performance summarizes a listener's ability to detect the presence of slower-changing amplitude variations applied to a faster-varying carrier signal. The modulation depth of the resulting combined signal can vary between 0 to 100% of the carrier signal with larger values indicating more extreme amplitude fluctuation. This research reports on the amount of modulation that can be detected as a function of different modulator and carrier frequencies, as well as overall stimulus level, as assessed via behavioral report.