Epidural Spinal Cord Stimulation for Blood Pressure and Pain
This study is looking at how permanent epidural spinal cord stimulation (SCS), a device implanted for chronic pain, might affect blood pressure. Researchers want to see if SCS can lower high blood pressure in people who also have chronic low back pain. They are also investigating if having higher blood pressure before SCS predicts better pain relief, and how different SCS settings affect brain and spinal cord activity. You might be able to join if you are between 18 and 89 years old, have chronic pain for over three months, and are scheduled for an SCS implant as part of your regular care. You cannot join if you have certain neurological conditions, a history of stroke, or cancer. The study aims to enroll 80 participants.
- Study design
- This interventional study plans to enroll 80 participants. It is not specified if it is randomized or blinded.
- What's involved
- You would visit a research lab and have a blood draw. Your blood pressure will be measured before and 4-6 weeks after your SCS implant.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your blood pressure will be measured at baseline (1 week before surgery) and again 4-6 weeks after your SCS implant.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Marshall Holland, MD · PRINCIPAL_INVESTIGATOR · The University of Alabama at Birmingham
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Arterial Blood Pressure ChangeBaseline (1 week pre-op)
The research team will assess systolic and diastolic blood pressure with an arm cuff.
- Arterial Blood Pressure ChangeVisit 2 (4-6 weeks post-op)
The research team will assess systolic and diastolic blood pressure with an arm cuff.