Collaborative Care for Anxiety and Depression in Epilepsy

This study is looking at two ways to help adults who have epilepsy along with anxiety or depression. One group will receive "collaborative care," which is a 24-week program where a care manager checks in every two weeks to discuss anxiety, depression, seizures, and side effects, and offers brief therapy. This care manager and a psychiatrist will work with your neurologist. The other group will receive "usual neurology care," which is your regular care without this extra program. The study wants to see if collaborative care improves your emotional quality of life after six months. You can join if you are 18 or older, have epilepsy, and experience anxiety or depression symptoms, and receive care at Atrium Health. The study is currently unclear on its recruitment status.

Study design
This is an interventional study comparing two approaches to care. It plans to enroll 60 adult participants.
What's involved
If you participate, you would either receive 24 weeks of collaborative care, including bi-weekly calls with a care manager, or continue with your usual neurology care.
Compensation
Not stated in the trial record.
Follow-up
Your emotional quality of life will be measured at Month 6.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05559749

Collaborative Care for Anxiety and Depression in Epilepsy

Active, Not Recruiting
NAAges 18+InterventionalSupportive care
Wake Forest University Health Sciences
~60 participants
Updated 2026-08-26 on ClinicalTrials.gov
What's tested:collaborative careusual neurology care

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
change in emotional quality of life subscale of the Quality of Life in Epilepsy Inventory (QOLIE-31) - between two groups
Measured over Month 6
Epilepsy
Anxiety
Depression
1 sites across 1 states
North Carolina1
  • Heidi M Munger Clary, MPH · PRINCIPAL_INVESTIGATOR · Wake Forest University Health Sciences

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Provision of signed and dated Informed Consent Form
Stated willingness to comply with all study procedures
Males and Females; Age \>= 18 years
\* Diagnosis of epilepsy: Epilepsy diagnosis based on neurology clinician impression or EEG findings
Anxiety or Depression symptoms
Receiving clinical neurological care at Atrium Health

Exclusion

Current participation in another treatment of intervention study
Cognitive limitations precluding completion of Anxiety and Depression self-report instruments on paper, electronically, or by interview
Comorbid medical condition with life expectancy less than 6 months
Not a good candidate for collaborative care due to:
Active ongoing treatment by a psychiatrist
Active suicidal ideation
History of past suicide attempt and:
receiving ongoing psychotherapy OR
has seen a psychiatrist in the past year
History of suicide attempt in the past year and:
currently prescribed 2 or more psychotropic medications for psychiatric indication (not merely as a hypnotic) AND not felt to be a good candidate for collaborative care based on the judgement of the investigators
Unstable drug or alcohol abuse
individuals who meet the above INC-EXC criteria and have completed the Control Arm of a collaborative care research study - NCT05559749 - NCT05353452 or
individuals who meet the above INC-EXC criteria except rather than having a diagnosis of Epilepsy; they have a diagnosis of functional neurological disorder with seizures
  • change in emotional quality of life subscale of the Quality of Life in Epilepsy Inventory (QOLIE-31) - between two groupsMonth 6

    adults with epilepsy and anxiety or depression symptoms - a higher score reflects a more favorable health state