Observational Study of Parkinson's Disease and Deep Brain Stimulation
This observational study is looking at people with Parkinson's Disease who have already had Deep Brain Stimulation (DBS) surgery. Researchers want to understand how different brain connections (pathway activation patterns) are linked to motor skills and thinking abilities (cognitive outcomes) after DBS. You might be able to join if you are at least 21 years old, have Parkinson's Disease, have a DBS system implanted, and have existing 7T brain imaging. The study aims to see how motor and cognitive outcomes are connected to these brain patterns 6 months after surgery. This information could help improve how DBS is used in the future.
- Study design
- This is an observational study planning to include 100 participants. It is not specified if it's randomized or blinded.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Motor and cognitive outcomes will be measured 6 months after surgery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Udall Project 1 Aim 4
At a glance
Conditions
NCT05568199
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University Of Minnesota
Minneapolis, Minnesotano site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Jerrold Vitek, MD, PhD · PRINCIPAL_INVESTIGATOR · University of Minnesota
Who to contact
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Inclusion
Exclusion
What this trial measures
- Motor association with pathway activation patterns6 months post surgery
associate pathway activation patterns with motor (UPDRS-III) outcome obtained during standard of care and research appointments.
- Cognitive outcome 1 association with pathway activation pattern6 months post surgery
associate pathway activation patterns with cognitive outcome obtained during standard of care and research appointments. One primary cognitive outcome measure will be the D-KEFS Letter Fluency test. Another primary cognitive measure will be the Stroop Color Word total score. Secondary measures will include the Beck Depression Inventory (BDI)-II and Apathy Scale total scores.
- Cognitive outcome 2 association with pathway activation pattern6 months post surgery
associate pathway activation patterns with cognitive outcome obtained during standard of care and research appointments. cognitive measure will be the Stroop Color Word total score.
- Cognitive outcome 3 association with pathway activation pattern6 months post surgery
associate pathway activation patterns with cognitive outcome obtained during standard of care and research appointments. cognitive measure will include the Beck Depression Inventory (BDI)-II
- Cognitive outcome 4 association with pathway activation pattern6 months post surgery
associate pathway activation patterns with cognitive outcome obtained during standard of care and research appointments. cognitive measure will include the Apathy Scale total scores.