This is an observational study looking at people with suspected or known genetic conditions related to allergic inflammation (like severe allergies), immune dysregulation (when the immune system doesn't work properly), or immune deficiency (when the immune system is weak). The study aims to understand the genetic and immune system causes of these conditions. You or your family members might be eligible if you have one of these conditions. The main goal is to identify the number of underlying traits that make someone susceptible to these conditions, measured over up to one year. This study does not involve any specific treatments or interventions.

Study design

This is an observational study planning to enroll up to 10,000 participants of all ages and genders.

What's involved

Blood, saliva, hair, fingernail clippings, and other samples may be collected. Outside medical records may be reviewed, and patient evaluations may be performed.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for up to one year to identify underlying susceptibility traits.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.