Sit-Stand Desk Study for Prediabetes and Obesity

This study is looking at whether using a sit-stand desk at work can help improve health for people with prediabetes, obesity, or metabolic syndrome. If you are between 18 and 79 years old, are overweight or obese (BMI of 25 or higher), and have a job where you sit for at least 75% of your workday, you might be able to join. You also need to be at risk for diabetes, meaning you have prediabetes (HbA1c between 5.7% and 6.4% or fasting glucose between 100 and 125 mg/dL). The study aims to see if using a sit-stand desk improves insulin sensitivity (how well your body uses insulin) after 6 months. Some participants will receive a sit-stand desk, while others will not.

Study design
This study is an interventional study with an estimated 198 participants. It compares a group using a sit-stand desk to a control group that receives no intervention.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, insulin sensitivity, is measured at 6 months from baseline.

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NCT05585190

Stand up for Your Health With a Sit-stand Desk

Recruiting
NAAges 18–79InterventionalPrevention
Medical College of Wisconsin
~198 participants
Updated 2026-05-04 on ClinicalTrials.gov
What's tested:ControlSit-Stand Desk at Work

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Insulin sensitivity (HOMA-IR)
Measured over change from baseline to 6 months
Pre Diabetes
Obesity
Metabolic Syndrome
Sedentary Behavior
1 sites across 1 states
Wisconsin1

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Eligibility criteria

Inclusion

Age 45 years or older
Family history of diabetes mellitus in a first-degree relative
Physical inactivity (no structured exercise activity)
History of gestational diabetes, hypertension, or dyslipidemia
African American, Alaska Native, American Indian, Asian American, Hispanic/Latino, Native Hawaiian, or Pacific Islander ethnicity
  • Insulin sensitivity (HOMA-IR)change from baseline to 6 months

    Determine if use of a sit-stand desk improves insulin sensitivity and ascertain if there is a dose-response relationship with changes in sedentary time.