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Collecting Samples from Healthy Volunteers for Myelodysplastic Syndromes Research

This study aims to collect blood, bone marrow, skin, saliva, and stool samples from healthy volunteers. Researchers need these samples to compare them with samples from people with Myelodysplastic Syndromes (MDS). MDS are blood stem cell disorders that can lead to blood cancers, and current treatments are limited. By comparing samples from healthy individuals to those with MDS, researchers hope to better understand how MDS develops. This understanding is crucial for finding new and more effective treatments. The study is open to healthy individuals aged 18 and older. The main goal is to create a database of these analyzed samples.

Study design
This is an observational study planning to enroll 1000 healthy volunteers. It is designed to collect and analyze biospecimens.
What's involved
You will be screened, have a physical exam, and blood and urine tests. Up to 5 types of samples (blood, bone marrow, skin, saliva, and stool) will be collected over one or more days within one month of screening.
Compensation
Not stated in the trial record.
Follow-up
The primary goal is to create a database of analyzed biospecimens, measured on an ongoing basis. No specific follow-up period for participants is mentioned.

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NCT05588154

Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies

Recruiting
Not specifiedAges 18+Observational
National Cancer Institute (NCI)
~1,000 participants
Updated 2026-07-23 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
create a database of analyzed biospecimens
Measured over ongoing

Conditions

Myelodysplastic Syndromes

Explore related trials

Healthy

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Kathy L McGraw, Ph.D. · PRINCIPAL_INVESTIGATOR · National Cancer Institute (NCI)

Who to contact

Danielle F Pinkiert, R.N.
[email protected]
(240) 858-7566
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Age \>= 18 years old
Healthy volunteers; the following confirmed by the Principal Investigator or designees based on recent (within 3 months before study intervention(s))
medical history
physical exam
complete blood count (CBC) within the normal reference range per the reporting clinical laboratory, established published literature and reports, or as deemed acceptable by the medical team based on the age and condition of the volunteer consistent with established clinical standards.
The ability of the participant to understand and the willingness to sign a written consent document.

Exclusion

Current immunosuppressive medication.
Any one of the following symptoms as declared by the participant at least one day per week within 3 months before study intervention(s) (Rome IV criteria \[36\])
Diarrhea characterized as frequent (\>2) loose stools
Constipation defined as \< 3 spontaneous bowel movements per week
Bloating and/or distention
Abdominal pain.
Participants with a history of the human immunodeficiency virus (HIV), hepatitis C (HCV), or hepatitis B (HBV) as confirmed by a seropositive blood test.
Pregnancy confirmed with beta-Human Chorionic Gonadotropin (Beta-HCG) serum or urine pregnancy test performed in women of childbearing potential at screening.
Breastfeeding participants.

What this trial measures

  • create a database of analyzed biospecimensongoing

    Collection of biospecimens from healthy volunteers.