Global Cardio Oncology Registry (G-COR)

This study, called G-COR, is collecting information from 5000 people to better understand how cancer treatments affect the heart. It focuses on patients with breast cancer, certain blood cancers (like lymphoma and leukemia), and those receiving immunotherapy (immune checkpoint inhibitors). The study will gather anonymous health information, including demographics, medical history, imaging results, lab tests, cancer treatments, and any heart-related events. The main goals are to identify risk factors for heart problems caused by cancer treatments and to develop tools to predict these risks. You might be able to join if you are 18 or older and are having a new consultation with a cardio-oncology specialist for one of the specified cancer types.

Study design
This is an observational study, meaning researchers will collect information without giving any specific treatments. It plans to include 5000 participants.
What's involved
You would allow researchers to collect your anonymous health data during your regular clinical follow-up appointments.
Compensation
Not stated in the trial record.
Follow-up
Researchers will track cardiotoxicity, new cardiovascular events, and cardiovascular death for 18 months after you join the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05598879

Global Cardio Oncology Registry

Recruiting
Not specifiedAges 18+Observational
The Cleveland Clinic
~5,000 participants
Updated 2026-05-12 on ClinicalTrials.gov
What's tested:anonymized data collection during programmed surveillance clinical follow up

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Cardiotoxicity
Measured over 18 months of prospective follow up
+2 more outcomes measured
Breast Cancer
Hematologic Malignancy
Immune Checkpoint Inhibitor-Related Myocarditis
Cardiotoxicity
Cardiovascular Diseases
1 sites across 1 states
Florida1
  • Diego Sadler, MD FACC · PRINCIPAL_INVESTIGATOR · The Cleveland Clinic

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Eligibility criteria

Inclusion

New cardio-oncology consultation for breast cancer patients, or
New cardio-oncology consultation for Hodgkin's or non-Hodgkin's lymphoma patients, or
New cardio-oncology consultation for acute or chronic leukemia patients, or
New cardio-oncology consultation for multiple myeloma or AL amyloidosis, or
New cardio-oncology consultations for immune check-point inhibitors cardiac evaluation.
All patients have to be 18 years old or older

Exclusion

Cardio-oncology patients who have previously had cardio-oncology evaluation and follow up by the investigators.
Minors less than 18 years old.
Inability or unwillingness to consent to participate
  • Cardiotoxicity18 months of prospective follow up

    Any new cardiac event occurring during or after cancer treatment

  • New cardiovascular events18 months of prospective follow up

    Heart failure, myocardial infarction, cardiac arrhythmias, syncope, coronary revascularization, heart transplant, cerebrovascular accident, peripheral arterial disease, hypertension, pulmonary hypertension. All events will be adjudicated according to standard clinical definitions.

  • Cardiovascular death.18 months of prospective follow up

    Death during or after cancer treatment, adjudicated to cardiovascular causes by treating physicians.