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Comparing Suture vs. Mesh for Incisional Hernia Repair

This study is comparing two ways to fix an incisional hernia (a bulge that happens after surgery): using stitches (suture repair) or using a surgical mesh (mesh repair). The main goal is to see if suture repair is just as good as mesh repair for your quality of life one year after surgery, specifically for hernias that are 2-6 cm wide. You could join if you are an adult over 18, have an incisional hernia that isn't an emergency, and haven't had mesh used in a previous hernia repair. The study's status is currently unclear, and it plans to enroll 154 participants.

Study design
This is a randomized controlled trial comparing two surgical methods, with participants blinded to which treatment they receive. It aims to enroll 154 participants.
What's involved
Participants will undergo incisional hernia repair and have their quality of life measured at 1 year after surgery.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for one year after their surgery to assess quality of life.

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NCT05599750

Suture Repair vs Mesh Repair for Incisional Hernia

Recruiting
NAAges 18+InterventionalTreatment
Clayton Petro
~154 participants
Updated 2026-01-07 on ClinicalTrials.gov
What's tested:Incisional hernia repair

At a glance

Recruiting sites
4 of 5 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Hernia specific quality of life
Measured over 1 year

Conditions

Incisional Hernia

Explore related trials

Incisional hernia

Where it's being run

5 sites across 4 states
Ohio2
Florida1
Illinois1
Tennessee1

Study leadership

  • Clayton Petro, MD · PRINCIPAL_INVESTIGATOR · The Cleveland Clinic

Who to contact

Clayton Petro, MD
[email protected]
2169242930
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults \>18 years old.
Anticipated hernia defect 2-6cm in width
Non-emergent case
CDC class I
Patients who previously underwent primary ventral hernia repair without the use of mesh
Incisional hernia

Exclusion

Emergent cases
Patients \< 18 years old
Patients who are pregnant
Patients who previously underwent a prior ventral hernia repair with mesh at the site of the intended repair. Abdominal mesh in separate locations would be allowed.
Ventral hernia \<2cm or \> 6 cm in width
Primary hernia
CDC wound class II-IV

What this trial measures

  • Hernia specific quality of life1 year

    Suture repair will be compared to mesh repair for incisional hernias 2-6cm with respect to quality of life using the Hernia-specific Quality of Life (HerQLes) summary score at one year postoperatively. This is reported as a score from 0-100 with higher numbers indicating better quality of life.