Gut Microbiome and Blood in Alzheimer's Patients and Caregivers
This observational study is looking at the connection between gut bacteria (microbiome) and blood markers in people with Alzheimer's disease (AD) and their spouses who are caregivers. Researchers believe that spousal caregivers might have similar gut and blood changes to AD patients, which could increase their risk of developing AD later. The study aims to see if there's a link between thinking abilities and these blood markers. You might be able to join if you are 65-90 years old and have AD, are a spouse of an AD patient, or are a healthy adult without dementia. The study will measure inflammation and amyloid (a protein linked to AD) in the blood. This study is currently recruiting 104 participants.
- Study design
- This is an observational study involving 104 participants. It is not a treatment study but rather looks at existing conditions.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Blood markers will be measured at one day.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Gut Microbiome and Blood Indices in Patients With AD and Their Spousal Caregivers
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Inflammation related biomarkersone day
interleukin (IL)-1β, IL-6, IL-10, IL-17, complement 3 (C3,) and YKL-40
- amyloid biomarkerone day
amyloid beta (Aβ)1-42
- ratio of Aβ1-42 and Aβ1-40one day
- total tau biomarkerone day
- phospho-tau at 181 or 217 biomarkerone day
- neurodegeneration related biomarkersone day
neurofilament light chain (NFL) and neurogranin
- serum short chain fatty acidsone day
acetic acid, propionic acid, isobutyric acid, butyric acid, valeric acid and hexanic acid