Deferiprone for Acute Myocardial Infarction

This study is testing a drug called Deferiprone to see if it can reduce the amount of extra iron in the heart after a heart attack (acute myocardial infarction). Researchers believe Deferiprone might work by affecting a process called RAF. You might be able to join if you are 18-79 years old, have had a specific type of heart attack (anterior wall STEMI), and received a procedure called primary PCI. The study will look at how well Deferiprone works after 6 months. This study is currently unclear about its recruitment status and plans to enroll 89 participants.

Study design
This is a randomized, controlled pilot study where neither you nor your doctors will know if you are receiving Deferiprone or a placebo (an inactive pill). It plans to include 89 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The study will assess the treatment's effectiveness at 6 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05604131

Cardiac MRI-guided Deferiprone Therapy for Acute Myocardial Infarction Patients

Recruiting
PHASE2Ages 18–79InterventionalTreatment
Rohan Dharmakumar
~89 participants
Updated 2026-04-08 on ClinicalTrials.gov
What's tested:Deferiprone TabletsPlacebo

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Treatment Efficacy
Measured over 6 months
Acute Myocardial Infarction Type 1

NCT05604131

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • IU Methodist Hospital (IUHealth)

    Indianapolis, Indianano site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Keyur P Vora, MD FACP FACC · PRINCIPAL_INVESTIGATOR · Medical Imaging Research Institute, Indiana University School of Medicine
  • Rohan Dharmakumar, PhD · PRINCIPAL_INVESTIGATOR · Medical Imaging Research Institute, Indiana University School of Medicine

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  • Treatment Efficacy6 months

    Percentage reduction of hemorrhagic zone iron content by cardiac magnetic resonance at 6 months relative to baseline