Meditation for Opioid-Treated Chronic Low Back Pain
This study is looking at how mindfulness meditation can help people with chronic low back pain who are also taking opioid medication. Researchers want to understand how meditation affects the brain's response to pain. You might be able to join if you are 18-65 years old, have chronic low back pain (pain on at least half the days in the past 6 months, with a usual pain score of 3 or higher on a 0-10 scale), and have been using prescription opioids for at least 3 months. The study will compare meditation training with usual care (like pain medication or physical therapy). Success will be measured by changes in brain activity related to blood oxygen levels (BOLD signaling) after 8 weeks. The current recruitment status is unclear.
- Study design
- This interventional study plans to enroll 188 participants. It compares meditation training with usual care for chronic low back pain.
- What's involved
- Participants will complete 8 sessions of meditation training or receive usual care. Brain activity will be measured at the beginning of the study and after 8 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be assessed at baseline and after 8 weeks of treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain
At a glance
Conditions
Where it's being run
2 sites across 2 statesStudy leadership
- Eric Garland, PhD · PRINCIPAL_INVESTIGATOR · University of Utah
- Fadel Zeidan, PhD · PRINCIPAL_INVESTIGATOR · University of California, San Diego
Who to contact
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What this trial measures
- Blood oxygenation level dependent (BOLD) signalingAt baseline and at post-treatment (8 weeks)
Changes in blood oxygenation levels to thermally noxious stimuli (48°C) will be assessed.