Cannabidiol for Alcohol Use Disorder

This study is looking at how Cannabidiol (CBD), a compound from the cannabis plant, might help people with Alcohol Use Disorder (AUD). Researchers want to see if taking a moderate dose of CBD, either full spectrum (with a tiny bit of THC) or broad spectrum (no THC), can reduce drinking, cravings for alcohol, and anxiety. You could join if you are at least 21 years old, have moderate AUD, and want to drink less. The study will compare CBD to a placebo (a pill with no active medicine) over 12 weeks to see if it helps reduce your alcohol use and cravings.

Study design
This is a double-blind, placebo-controlled study, meaning neither you nor the researchers will know if you are receiving CBD or the placebo. About 180 participants will be randomly assigned to one of the treatment groups.
What's involved
If you are eligible, you will receive one of the study conditions for 12 weeks. The study will measure changes in your drinking, alcohol craving, and alcohol use disorder during this time.
Compensation
Not stated in the trial record.
Follow-up
The main changes in drinking, alcohol use disorder, and craving will be measured over 12 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05613608

Alcohol Use Disorder and Cannabidiol

Recruiting
PHASE2Ages 21+InterventionalTreatment
University of Colorado, Denver
~180 participants
Updated 2026-06-15 on ClinicalTrials.gov
What's tested:CannabidiolPlacebo

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Drinks per Drinking Day
Measured over 0-12 weeks
+2 more outcomes measured
Alcohol Use Disorder
1 sites across 1 states
Colorado1
  • Kent Hutchison, PhD · PRINCIPAL_INVESTIGATOR · University of Colorado, Denver

Opens a ready-to-send draft in your own email app — review before sending.

  • Change in Drinks per Drinking Day0-12 weeks

    The Time Line Follow Back is a calendar-assisted measure that can be used to assess alcohol, tobacco, cannabis, and other substance use. The investigators will use this measure to create the Drinks per Drinking Day variable.

  • Change in Alcohol Use Disorder0-12 weeks

    The AUDIT consists of ten questions that cover such domains as alcohol consumption, drinking behavior, adverse psychological reactions, and alcohol-related problems.

  • Change in Alcohol Craving0-12 Weeks

    The Penn Alcohol Craving Scale (PACS) will be used to assess changes in alcohol craving.