UNC Pleural Fluid Registry for Lung and Breast Cancer

This study is creating a registry of pleural fluid (fluid around the lungs) samples from patients with lung cancer, breast cancer, lung infection, or other conditions causing fluid buildup. Researchers will collect these samples to better understand how diseases work, develop new tests, and find new ways to treat illnesses in the future. You can join if you are 18 or older, have pleural fluid that needs to be drained, and have a diagnosis of lung infection or cancer. The study aims to build this registry over 32 years. The current recruitment status is unclear.

Study design
This is an observational study, meaning researchers will collect information and samples without giving any specific treatments. The study plans to enroll up to 9999 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

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NCT05620329

UNC Pleural Fluid Registry

Recruiting
Not specifiedAges 18+Observational
UNC Lineberger Comprehensive Cancer Center
~9,999 participants
Updated 2025-10-16 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Creation of a pleural fluid registry
Measured over 32 years
Lung Cancer
Lung Infection
Breast Cancer
Malignant Pleural Effusion
Empyema
1 sites across 1 states
North Carolina1
  • Jason Akulian · PRINCIPAL_INVESTIGATOR · UNC Lineberger Comprehensive Cancer Center

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Eligibility criteria

Inclusion

Patients who are 18 years or older
Inpatients and outpatients
Diagnosed with pleural fluid, are referred for and undergo clinically indicated drainage who have clinical evidence of:
pulmonary infection (such as fever, leukocytosis, new or worsening infiltrate on chest x-ray, or clinical deterioration) with effusion
malignancy

Exclusion

A subject will not be eligible for inclusion in this registry if, in the investigator's (or treating clinician's) opinion, the patient has any concurrent medical condition that may preclude their ability to undergo pleural fluid drainage safely.
Incarcerated individuals
  • Creation of a pleural fluid registry32 years

    Biological specimens and corresponding clinical data from subjects will be collected during standard of care procedures and medical record abstraction to support the creation of a pleural fluid registry.