Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder
This study is testing if a combination of fMRI neurofeedback and/or TMS (Transcranial Magnetic Stimulation) can help people receiving treatment for Alcohol Use Disorder. fMRI neurofeedback uses real-time brain imaging to help you learn to control brain activity related to craving. TMS uses magnetic pulses to stimulate specific brain areas. The study aims to see if these interventions can reduce alcohol use and craving, and improve daily functioning. You may be able to join if you are between 19 and 65 years old and are currently receiving treatment for Alcohol Use Disorder. The study plans to enroll 90 participants, but its current status is unclear.
- Study design
- This interventional study plans to enroll 90 participants. It is not specified if it is randomized or blinded.
- What's involved
- After an initial visit, you will have weekly intervention sessions for four weeks. You will also have remote monthly follow-ups for up to 12 months, and two in-person MRI follow-ups at 6 and 12 months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for changes in alcohol use, craving, and community functioning for up to 53 weeks (approximately one year).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Samantha J Fede, PhD · PRINCIPAL_INVESTIGATOR · Auburn University
Who to contact
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What this trial measures
- Change in Alcohol Use over TimeAssessed at weeks: 1 (baseline), 2-5 (intervention sessions, pre and post), 9, 13, 17, 21, 25, 33, 37, 41, 45, 49, 53 (follow-ups)
Alcohol Timeline Followback (alc-TLFB)
- Change in Alcohol Craving over TimeAssessed at weeks: 1 (baseline), 2-5 (intervention sessions, pre and post), 9, 13, 17, 21, 25, 33, 37, 41, 45, 49, 53 (follow-ups)
Alcohol Craving Questionnaire (ACQ)
- Change in Community Functioning over TimeAssessed at weeks: 1 (baseline), 2-5 (intervention sessions), 9, 13, 17, 21, 25, 33, 37, 41, 45, 49, 53 (follow-ups)
Drinker Inventory of Consequences (DrInC)
- Change in Employment Status over TimeAssessed at weeks: 1 (baseline), 2-5 (intervention sessions), 9, 13, 17, 21, 25, 33, 37, 41, 45, 49, 53 (follow-ups)
self-reported employment status
- Change in Aggression and Victimization over TimeAssessed at weeks: 1 (baseline), 2-5 (intervention sessions), 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 57 (follow-ups)
Revised Conflict Tactics Scales (CTS-R)
- Change in Antisocial Behavior over TimeAssessed at weeks: 1 (baseline), 2-5 (intervention sessions), 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 57 (follow-ups)
number of self-reported contacts with the police, convictions, and other criminal behaviors
- Change in Brain Activity during Alcohol Cue Presentation over TimeAssessed at weeks: 1 (baseline), 5 (post final intervention), 29 and 57 (follow-ups)
Measured via fMRI; standard alcohol cue reactivity
- Change in Brain Activity during Simultaneous Sociomoral & Alcohol Cue Presentation over TimeAssessed at weeks: 1 (baseline), 5 (post final intervention), 29 and 57 (follow-ups)
Measured via fMRI; alcohol-cued sociomoral processing