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High Intensity Interval Training (HIIT) for Older Veterans

This study is looking at how different types of exercise can help older veterans who are experiencing frailty. Frailty means you're more likely to have health problems from aging. Researchers want to see if High Intensity Interval Training (HIIT), either at a center or at home, can improve your physical fitness. There's also a control group that will do stretching. The main goal is to measure changes in your sub-maximal oxygen uptake (VO2max), which shows how well your body uses oxygen during exercise, after 12 weeks. You might be able to join if you are 65 or older, medically cleared for exercise, and are not severely frail. The current status of this study is unclear, and it plans to enroll 200 participants.

Study design
This is an interventional study comparing center-based stretching, center-based HIIT, and home-based HIIT. It plans to enroll 200 participants.
What's involved
Participants will have their sub-maximal oxygen uptake tested at the beginning and after 12 weeks.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 weeks, based on the primary endpoint timeframe.

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NCT05625204

High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older Veterans

Recruiting
NAAges 65+InterventionalTreatment
VA Office of Research and Development
~200 participants
Updated 2025-12-12 on ClinicalTrials.gov
What's tested:Center based attention (stretching only) controlCenter based HIITHome based HIIT

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Sub-maximal oxygen uptake test (VO2max)
Measured over Change from baseline to endpoint at 12 weeks

Conditions

Frailty

Explore related trials

Frailty

Where it's being run

2 sites across 1 states
Missouri2

Study leadership

  • Bruce R. Troen, MD · PRINCIPAL_INVESTIGATOR · Kansas City VA Medical Center, Kansas City, MO

Who to contact

Kenneth L Seldeen, PhD
[email protected]
(716) 888-4869
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Ages 65 years and older
Male and female, any race
Medically cleared for exercise
Non-frail or pre-frail (frailty score \< 3)
Ability to use a recumbent exercise bike

Exclusion

Severe co-morbidity: COPD (GOLD stage IV), CKD ( stage 3)), severe HTN (180 mmHg/120 mmHg)
VA-SLUMS score 20 or lower (Cognition)

What this trial measures

  • Sub-maximal oxygen uptake test (VO2max)Change from baseline to endpoint at 12 weeks

    Participants are asked to exercise on an upright exercise bike as the resistance increases over time. During the exercise, participants are asked to breath through a mask that is connected to a oxygen and carbon dioxide measuring device. The assessment last for approximately 5-10 minutes and provides data the pertain to an individuals lung capacity, breathing rate, and endurance.