ExoLuminate Study for Early Detection of Pancreatic Cancer

The ExoLuminate study is looking for people aged 18 and older who are at high risk for pancreatic cancer or have symptoms that suggest it. This study is testing a new blood test called ExoVerita™ that aims to find pancreatic cancer (pancreatic ductal adenocarcinoma or PDAC) earlier. The ExoVerita™ test works by isolating tiny particles called extracellular vesicles (EVs) from your blood and looking for specific protein markers. The goal is to see if this new test can detect pancreatic cancer as well as or better than current methods. The study is currently recruiting participants.

Study design
This is an observational study planning to enroll at least 1000 adults across the U.S. It is not specified if it is randomized or blinded.
What's involved
You would provide blood samples at specific times. The study will follow your data for two years after the initial three-year recruitment period.
Compensation
Not stated in the trial record.
Follow-up
Your data will be collected for up to two years after the initial three-year recruitment period, or until a diagnosis is made.

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NCT05625529

ExoLuminate Study for Early Detection of Pancreatic Cancer

Recruiting
Not specifiedAges 18+Observational
Biological Dynamics
~1,000 participants
Updated 2025-07-28 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Clinical performance of ExoVerita™ assay
Measured over 36 months or until diagnostic resolution
Pancreas Cancer
Exosomes
Extracellular Vesicles
Pancreatic Neoplasms
1 sites across 1 states
California1
  • Harmeet Dhani, MD, M.Sc · PRINCIPAL_INVESTIGATOR · Biological Dynamics

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Eligibility criteria

Inclusion

≥18 years old.
Meeting criteria for one of the study cohorts.
Capable of giving informed consent.
Able to provide a blood sample.

Exclusion

\< 18 years old.
Pregnancy.
Active cancer (other than pancreatic cancer) and/or undergoing treatment for an active cancer diagnosis (except for skin malignancies).
Prior organ transplant or bone marrow transplant.
History of fainting or other adverse effects when blood is drawn.
Any condition that, in the opinion of the investigator, should preclude enrollment.
  • Clinical performance of ExoVerita™ assay36 months or until diagnostic resolution

    Specificity