Electrical Stimulation for Glaucoma and Optic Nerve Diseases

This study is testing a device called Repetitive, Transorbital Alternating Current Stimulation (rtACS) to see if long-term electrical stimulation is safe and effective for treating open-angle glaucoma. Open-angle glaucoma is a condition where the nerves in the back of your eye die off faster than expected. You may be able to join if you are at least 18 years old and have a diagnosis of glaucoma with a specific level of vision loss (Mean Deviation worse than -3 on a visual field test). The study will measure changes in your vision over 6 months to see if the treatment is successful. The current status of this study is unclear.

Study design
This is an open-label study, meaning both you and the study team will know you are receiving the active treatment. It plans to enroll 40 participants.
What's involved
You would receive treatment every other day via a headband that delivers electrical stimulation. Your visual field will be assessed at the beginning and then again over 6 months.
Compensation
Not stated in the trial record.
Follow-up
Your vision will be monitored for 6 months after starting the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05626426

Electrical Stimulation for the Treatment of Optic Neuropathies

Recruiting
NAAges 18+InterventionalTreatment
Stanford University
~40 participants
Updated 2025-07-08 on ClinicalTrials.gov
What's tested:Repetitive, Transorbital Alternating Current Stimulation (rtACS)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from baseline in visual field assessed by Humphrey Visual Field Index (VFI).
Measured over Baseline through 6 months
+1 more outcome measured
Glaucoma
Glaucoma, Open-Angle
Optic Nerve Diseases
1 sites across 1 states
California1
  • Jeffrey L Goldberg, MD PhD · PRINCIPAL_INVESTIGATOR · Stanford University

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  • Change from baseline in visual field assessed by Humphrey Visual Field Index (VFI).Baseline through 6 months
  • Change from baseline in visual field assessed by Humphrey Mean Deviation (MD).Baseline through 6 months