Circadian Time Restricted Eating for Cardiometabolic Health and Weight Loss

This study is looking into how the timing of your meals, specifically a personalized schedule called Circadian Based Time Restricted Eating, affects your heart health (cardiometabolic health) and weight. Researchers want to see if eating at certain times based on your body's natural clock can improve these areas. You might be able to join if you are between 18 and 40 years old, are overweight or obese (BMI of 27 or higher), and are generally healthy. The study will measure changes in your blood pressure and heart rate over 46 days to see if the intervention is successful. The current status of the study is unclear.

Study design
This is an interventional study with a planned enrollment of 10 participants. It is a 46-day prospective cohort study.
What's involved
You would participate in a 46-day study that includes both field and in-laboratory data collection. You would follow a personalized eating schedule.
Compensation
Not stated in the trial record.
Follow-up
Changes in blood pressure and heart rate are measured at 46 days.

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NCT05628012

Circadian Time Restricted Eating

UNKNOWN
NAAges 18–40Interventional
Oregon Health and Science University
~10 participants
Updated 2024-04-03 on ClinicalTrials.gov
What's tested:Circadian Based Time Restricted Eating

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Dim-Light Melatonin Onset
Measured over 7.5 hours
+7 more outcomes measured
Circadian Rhythm
Cardiometabolic Health
Weight Loss
Cardiovascular Health
Time Restricted Feeding
1 sites across 1 states
Oregon1

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  • Dim-Light Melatonin Onset7.5 hours

    Saliva samples will be collected during baseline week and will be assayed for melatonin using standardized assays. Dim-light melatonin onset will be calculated using the linear interpolated point in time in which each participant's melatonin crosses and remains elevated above a 4pg/mL threshold.

  • Changes in Blood Pressure46 days

    Changes in resting blood pressure will be measured every \~30 minutes via ambulatory blood pressure machines for up to 48-hours during weeks 0, 1, 5, 10, and 16. Blood pressure patterns during the day and night will be assessed, as well as a contrast of day and night time blood pressure levels. Examined using planned comparison dependent t-tests between the baseline and the five-week visit. These data will be used to calculate mean differences and standard deviations between the control and experimental group for future experiments.

  • Changes in Heart Rate46 days

    Heart rate will be measured every \~30 minutes via a blood pressure cuff. Examined using planned comparison dependent t-tests between the baseline and the five-week visit. These data will be used to calculate mean differences and standard deviations between the control and experimental group for future experiments.

  • Changes in Hemoglobin A1c46 days

    Changes in Hemoglobin A1c (HbA1c) will be measured during weeks 1, 5, and 16. Examined using planned comparison dependent t-tests between the baseline and the five-week visit. These data will be used to calculate mean differences and standard deviations between the control and experimental group for future experiments.

  • Changes in Total Cholesterol46 days

    Changes in total cholesterol will be measured during weeks 1, 5, and 16. Examined using planned comparison dependent t-tests between the baseline and the five-week visit. These data will be used to calculate mean differences and standard deviations between the control and experimental group for future experiments.

  • Changes in LDL and HDL cholesterol46 days

    Changes in HDL and LDL cholesterol will be measured during weeks 1, 5, and 16. Examined using planned comparison dependent t-tests between the baseline and the five-week visit. These data will be used to calculate mean differences and standard deviations between the control and experimental group for future experiments.

  • Changes in Triglycerides46 days

    Changes in triglycerides will be measured during weeks 1, 5, and 16. Examined using planned comparison dependent t-tests between the baseline and the five-week visit. These data will be used to calculate mean differences and standard deviations between the control and experimental group for future experiments.

  • Changes in Glucose46 days

    Changes in glucose will be measured during weeks 1, 5, and 16. Examined using planned comparison dependent t-tests between the baseline and the five-week visit. These data will be used to calculate mean differences and standard deviations between the control and experimental group for future experiments.