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Stepped Care for PTSD After Injury

This study is testing a Stepped Collaborative Care program for people who have experienced a physical injury and are showing symptoms of Posttraumatic Stress Disorder (PTSD). This program involves case management, behavioral support, and recommendations for medications, with 24/7 phone support for six months. It's being compared to the usual care, which includes standard screening and referrals. The goal is to see if Stepped Collaborative Care can reduce PTSD symptoms and lower the number of emergency room visits over time. You might be able to join if you are 18 or older, have been injured, meet certain risk criteria, and speak English or Spanish. The study plans to enroll 424 people, but its current status is unclear.

Study design
This is a randomized study comparing two approaches to care. It aims to include 424 participants.
What's involved
You would be followed for changes in PTSD symptoms and emergency department use from your injury admission up to 12 months later.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months after their injury admission.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05632770

A Deployment Focused Pragmatic Trial of Optimal Stepped Care Intervention Targeting PTSD and Comorbidity for Acutely Hospitalized Injury Survivors Treated in US Trauma Care Systems

Active, Not Recruiting
NAAges 18+InterventionalTreatment
University of Washington
~424 participants
Updated 2026-04-29 on ClinicalTrials.gov
What's tested:Stepped Collaborative CareAmerican College of Surgeons (ACS) Required Screening and Referral (Usual Care)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Posttraumatic Stress Disorder (PTSD) symptoms change over time
Measured over Change in symptoms at baseline injury admission and 1-, 3-, 6-, and 12-months post-injury follow-up
+1 more outcome measured

Conditions

PTSD
Physical Injury

Explore related trials

Physical InjuryPost-Traumatic Stress Disorder

Where it's being run

1 sites across 1 states
Washington1

Study leadership

  • Douglas Zatzick, MD · PRINCIPAL_INVESTIGATOR · University of Washington

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Injured patients ≥18 years of age
Meet ≥ 3 of 10 risk domain criteria in electronic health records (EHR) screen
Score of ≥ 30 on DSM-5 PTSD Checklist (PCL) score or score of ≥ 35 on DSM-IV PTSD Checklist (PCL) .
Speak English and/or Spanish

Exclusion

Age \<18
Not admitted for a traumatic injury
Speak a language other than English and/or Spanish
Acutely suicidal/admitted for a suicide attempt
Cognitively impaired
Incarcerated
Acutely psychotic
Not a resident of Washington, California, Alaska, Oregon, Idaho, Montana, or Nevada
Less than 2 pieces of contact information
Prior history of violence, such that study staff may not be safe
Patient with overwhelming psychiatric distress and not advisable/will not tolerate randomization to control condition
Most recent COVID-19 test positive

What this trial measures

  • Posttraumatic Stress Disorder (PTSD) symptoms change over timeChange in symptoms at baseline injury admission and 1-, 3-, 6-, and 12-months post-injury follow-up

    The investigators will use the DSM-5 PTSD Checklist (PCL-5) and DSM-IV PTSD Checklist (PCL-IV). The scoring of the PCL-5 scale ranges from a minimum of 0 to a maximum of 80, with higher scores indicating a worse outcome. The measure can also provide a rating of symptoms consistent with a diagnosis of PTSD.

  • Emergency department utilization change over timeBaseline injury admission to 12-months post-injury follow-up

    Number of emergency visits will be assessed using the Emergency Department Information Exchange (EDIE). More emergency visits are indicative of a worse outcome.