The WISER Study: Web-Based Methods for Enhancing Resilience

This study, called The WISER Study, is looking into whether web-based tools can help improve your well-being. If you join, you'll try out one or more brief positive psychology tools online. These tools ask you to think about positive experiences or do activities like writing a thank-you letter. The study team wants to see how these tools affect stress, depression, and burnout in adults. You'll complete short surveys before and after using the tools, and again at later times to measure changes in emotional exhaustion. Adults aged 18 and over can participate. The study aims to enroll 8000 people and is currently unclear on its recruitment status.

Study design: This is an interventional study testing web-based behavioral tools, with a planned enrollment of 8000 participants.
What's involved: You will engage in one or more online positive psychology well-being tools and complete brief surveys before, after, and at follow-up periods.
Compensation: Not stated in the trial record.
Follow-up: You will be followed for changes in emotional exhaustion at Day 8, and 1, 6, and 12 months after starting the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

The WISER Study: Web Based Methods for Enhancing Resilience

Recruiting

NAAges 18+InterventionalTreatment

Duke University

~8,000 participants

Updated 2026-04-08 on ClinicalTrials.gov

What's tested:WISER

At a glance

Recruiting sites

1 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Change in Emotional Exhaustion as measured by the 5-item Emotional Exhaustion Scale

Measured over Baseline, Day 8, and 1, 6, and 12 month follow-ups

Conditions

Burnout

NCT05636072

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

Duke University Health System
Durham, North Carolinastudy coordinator listed
Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

John B Sexton, PhD · PRINCIPAL_INVESTIGATOR · Duke

Who to contact

John B Sexton, PhD

[email protected]

+1 919 681 4949

Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

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Eligibility criteria

Inclusion

Adults 18 and over are considered eligible for the study. A sub-sample will include employees (including but not limited to frontline caregivers, support staff and management) of the Duke University Health System, as well as external health systems. All participants will be invited to participate in one or more of the online tools. The investigators will allow the participation of any clinical areas/healthcare worker groups whose leaders express interest in building resilience. The investigators are targeting healthcare workers for recruitment in the study, but adults 18+ are eligible to participate in any of these tools. Identification as a healthcare worker or not is part of data collection in every tool.

Exclusion

Adults who are not proficient in English, do not have basic computer skills, or who have prohibitive vision or hearing disabilities will be excluded from this study as they will be incapable of full participation in the intervention and/or the survey process.

What this trial measures

Change in Emotional Exhaustion as measured by the 5-item Emotional Exhaustion ScaleBaseline, Day 8, and 1, 6, and 12 month follow-ups
Survey scores are measured on a 1-5 Likert-like agreement scale.

Trialytics