This study, called TROOP, is looking at the best way to give blood transfusions to severely injured patients who are bleeding heavily. It compares two approaches: giving unseparated whole blood (called Low-Titer Group O Whole Blood, or LTOWB) or giving separate blood parts (like red blood cells, plasma, and platelets). The goal is to see which method helps more patients survive within the first 6 hours after receiving the transfusion. You might be able to join if you are an adult trauma patient over 15 years old, weighing more than 50 kg, and are already receiving a blood transfusion due to severe bleeding. The study plans to enroll 1100 participants, but its current status is unclear.

Study design

This study is an interventional trial planning to enroll 1100 participants. Patients will be randomly assigned to receive either whole blood or separate blood components.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The primary outcome, 6-hour mortality, is measured within the first 6 hours after randomization.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.