Continuous Intercostal Nerve Block for Multiple Rib Fractures

This study is looking at how well a continuous intercostal nerve block (CINB) with Ropivacaine helps patients with multiple broken ribs. You could be eligible if you are at least 18 years old and have two or more broken ribs. The study compares CINB plus standard pain medicine (non-steroidal anti-inflammatory drugs and opioids) to standard pain medicine alone. Researchers want to see if CINB can reduce how long patients need to stay in the hospital. The study is currently recruiting 180 participants, but its overall status is unclear.

Study design
This is a prospective, randomized study comparing two treatment groups. It is not blinded, meaning both you and your doctors will know which treatment you are receiving. The study plans to enroll 180 participants.
What's involved
Patients in the CINB group will have a catheter placed to deliver Ropivacaine. Patients in the other group will receive standard pain medications. The study measures your length of hospital stay.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, length of hospital stay, is measured at 7 days.

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NCT05642026

INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures

Recruiting
PHASE4Ages 18+InterventionalTreatment
Zachary Warriner
~180 participants
Updated 2025-10-07 on ClinicalTrials.gov
What's tested:RopivacaineNon steroidal anti-inflammatory drug and opioids

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Length of hospital stay
Measured over 7 days
Rib Fractures
1 sites across 1 states
Kentucky1
  • Zachary Warriner, MD · PRINCIPAL_INVESTIGATOR · University of Kentucky

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Eligibility criteria

Inclusion

Subjects will be at least 18 years old
Subjects will have 2 or more identified rib fractures
Subjects will be willing to provide informed consent for procedure
Subjects will be identified as appropriate for initiation of continuous nerve block therapy for treatment of rib fracture associated pain.

Exclusion

Documented allergy to study medication
Epidural catheter use
Prisoners
Refusal of CINB therapy
  • Length of hospital stay7 days

    time from randomization until the time of discharge