Observational Study of Exposure to Environmental Toxicants Among Firefighters

This observational study is looking at how firefighters are exposed to harmful chemicals (toxicants) from fire smoke. Researchers will collect samples from firefighters before and after they respond to a fire call. They want to see how the levels of these chemicals change. You can join if you are a career or volunteer firefighter, over 18 years old, and willing to provide samples. The study aims to understand these chemical exposures over 48 months. The study is currently unclear on its recruitment status and plans to enroll 60 participants.

Study design
This is an observational study with 60 participants. It's designed to compare samples from the same person before and after fire exposure.
What's involved
You would provide three sample collections, including buccal cells (from inside your cheek) and urine samples, before and after a fire call.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, studying biomarker levels, is measured at 48 months.

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NCT05643014

Observational Study of Exposure to Environmental Toxicants Among Firefighters

Recruiting
Not specifiedAges 18+Observational
Masonic Cancer Center, University of Minnesota
~60 participants
Updated 2026-03-12 on ClinicalTrials.gov
What's tested:Sample collection

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Studying biomarker levels in firefighters pre and post fire call.
Measured over 48 months
Healthy
1 sites across 1 states
Minnesota1

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Eligibility criteria

Inclusion

Firefighter (career or volunteer)
Over 18 years of age
Able to provide written voluntary consent

Exclusion

Unwilling to provide a pre and post-exposure urine sample
Current cancer diagnosis
Tobacco use within the last 1 year (verified by urinary TNEs)
  • Studying biomarker levels in firefighters pre and post fire call.48 months

    The investigators will evaluate the differences between mean pre-exposure biomarker levels and post-exposure levels in urine and buccal samples collected within 24 hours post-exposure and 1-week post-exposure respectively using t-tests to test for statistical significance.