Palliative Care for Blood Cancers During Cellular Therapy

This study is testing if a special type of care called palliative care (PEACE) can improve the quality of life and experiences for people with blood cancers like Lymphoma, Leukemia, or Multiple Myeloma. You might be eligible if you are 18 or older, have a blood cancer, and are receiving a specific type of treatment called autologous adoptive cellular therapy (ACT) at MGH. The study aims to see how many eligible people enroll in the PEACE intervention. The current status of the study is unclear, but it plans to enroll about 90 people.

Study design
This is a randomized study, meaning participants are assigned to a group by chance, with about 90 participants planned.
What's involved
Participation in this research study is expected to last for up to 2 years.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

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NCT05646576

Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy

Recruiting
NAAges 18+InterventionalSupportive care
Massachusetts General Hospital
~90 participants
Updated 2026-04-21 on ClinicalTrials.gov
What's tested:Palliative CareUsual Care

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of Eligible Participants Enrolled to Palliative Care Intervention (PEACE) (Feasibility)
Measured over 1 day
Hematologic Malignancy
Blood Cancer
Lymphoma
Leukemia
Multiple Myeloma
1 sites across 1 states
Massachusetts1
  • Patrick C Johnson, MD · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

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Eligibility criteria

Inclusion

Age 18 years or older.
Ability to complete surveys in English or with assistance of an interpreter.
Diagnosis of a hematologic malignancy.
Receiving autologous adoptive cellular therapy (ACT) at MGH with an FDA approved cellular therapy product.

Exclusion

Impaired cognition or uncontrolled mental illness that prohibits study compliance based on the oncology clinician assessment.
Already receiving palliative care (PC).
  • Percentage of Eligible Participants Enrolled to Palliative Care Intervention (PEACE) (Feasibility)1 day

    Defined as at least 60% of eligible participants enrolling in the study, and among those enrolled and randomized to PEACE, 80% receiving PEACE as intended.