This observational study, called RESOLVE, is looking at people who have had a kidney transplant and were previously diagnosed with Focal Segmental Glomerulosclerosis (FSGS) or Minimal Change Disease (MCD). Researchers want to understand why these conditions sometimes come back after a transplant and how they affect the new kidney. They will collect information and samples like urine, blood, and kidney tissue to build a biobank for future research. The study aims to track how long it takes for FSGS to return and how long the transplanted kidney continues to work, both measured up to two years after transplant. You can join if you had a transplant in 2000 or later and had FSGS or MCD in your original kidneys. You cannot join if your diagnosis was due to another condition like lupus.

Study design

This is an observational study with a planned enrollment of 300 participants. It will collect both past and current information, as well as biological samples.

What's involved

Participants will provide biospecimens (like urine, blood, saliva, kidney tissue) and data will be collected. The study will track outcomes for up to two years after transplant.

Compensation

Not stated in the trial record.

Follow-up

The study will measure outcomes like time to FSGS recurrence and time to graft failure for up to 2 years after transplant.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.