Observational Study of Medtronic Percept DBS in Parkinson's Disease
This study is looking at how the Medtronic Percept™ DBS system, used for Parkinson's disease, affects movement and brain activity. Researchers will observe people who already have this system implanted and have been using it for at least three months. They want to understand how brain signals (local field potentials or LFPs) relate to changes in walking and balance during daily activities. The study aims to see if there's a connection between these brain signals and how well you move, especially your leg function and posture. The main goals are to measure your walking speed, stride length, and brain activity after 30 days. This is an observational study, meaning there are no new treatments given. The study plans to enroll 36 participants.
- Study design
- This is an observational study, meaning no new treatments are given. It plans to include 36 participants.
- What's involved
- You would be observed for a minimum of 4 weeks, with measurements taken at 30 days.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements for the main goals are taken at 30 days.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Udall Project 2 Aim 2A&C
At a glance
Conditions
NCT05656586
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of Minnesota
Minneapolis, Minnesotastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
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Inclusion
Exclusion
What this trial measures
- Peak negative power30 day
A servo-controlled ankle manipulandum will be used to obtain objective measures of resistance about the dorsiflexion/plantar flexion axis (range of motion approximately 5 deg. dorsiflexion to 30 deg. plantar flexion; frequency = 1.5 Hz). Two conditions will be tested: passive movement with and without an activation maneuver on the contralateral side (repetitive tapping of the toe or heel).
- Stride length30 days
The spatial and temporal parameters of overground steady-state gait will be assessed in the lab or derived from the wearable device (mPower)
- Alpha power during standardized daily gait assessment30 days
The participant will use their DBS device patient programmer to record a time stamp and capture LFPs using the implanted Medtronic Percept™ device during the standardized daily gait assessments.
- cadence30 days
The spatial and temporal parameters of overground steady-state gait will be assessed in the lab or derived from the wearable device (mPower)