FES BPET-DBT Imaging for Newly Diagnosed Breast Cancer
This study is looking at a new way to image breast cancer using a special device that combines two imaging techniques: dedicated Breast Positron Emission Tomography (BPET) and Digital Breast Tomosynthesis (DBT). You would receive an injection of a radioactive tracer called [18F]-Fluoroestradiol (FES) before the imaging. This study is for women aged 18 or older who have recently been diagnosed with estrogen-receptor (ER) positive breast cancer and have at least one tumor that is 1.0 cm or larger. Researchers want to see how well the FES BPET-DBT imaging works to show the cancer and the quality of the images. Up to 20 participants are planned for this study, but the current recruitment status is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific intervention (the imaging with FES BPET-DBT). It plans to enroll up to 20 participants.
- What's involved
- You would undergo an imaging session with the FES BPET-DBT device after receiving an intravenous injection of FES. The study will assess FES uptake, image quality, and artifacts at 6 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcomes, such as FES uptake and image quality, will be measured at 6 weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
FES BPET-DBT in Newly Diagnosed Breast Cancer
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Christine Edmonds, MD · PRINCIPAL_INVESTIGATOR · Abramson Cancer Center at Penn Medicine
Who to contact
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What this trial measures
- Uptake of FES on BPET6 weeks
Different types of SUV measurements (e.g. Max, Mean and Peak) may be tested to identify the optimal method for analyses for future studies of FES-BPET/DBT.
- Image quality6 weeks
The image quality of the study DBT will be compared to the clinical DBT in terms of image quality
- Image artifacts6 weeks
Image artifacts on study DBT will be compared to clinical DBT
- Parenchymal appearance6 weeks
The parenchymal appearance of the study DBT will be compared to the clinical DBT
- Tumor size and extent6 weeks
The size/extent of tumor on the study DBT will be compared to the clinical DBT