Cell-free DNA (cfDNA) for Lymphoma Patients in Texas Community Centers

This study is looking at how useful and practical it is to collect cell-free DNA (cfDNA) from lymphoma patients in community centers across Texas. cfDNA is DNA that travels freely in your blood and can be easily collected with a simple blood draw from your vein. Researchers want to see if cfDNA can help identify changes in your cancer and detect any remaining disease after treatment. The main goal is to see how long patients live overall (Overall Survival). You may be able to join if you are at least 18 years old, have diffuse large B-cell lymphoma requiring treatment, and can provide written consent. The study plans to enroll 517 participants.

Study design
This interventional study plans to enroll 517 participants with diffuse large B-cell lymphoma. It is designed to test the feasibility and clinical utility of cell-free DNA.
What's involved
You would have blood samples taken to collect cell-free DNA (cfDNA) before and after your lymphoma treatment.
Compensation
Not stated in the trial record.
Follow-up
Your overall survival will be measured through study completion, which is an average of 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05676450

Feasibility and Clinical Utility of Cell-free DNA (cfDNA) in Identifying Actionable Alterations and Minimal Residual Disease for Lymphoma Patients Across Community Centers in Texas

Recruiting
NAAges 18+InterventionalDiagnostic
M.D. Anderson Cancer Center
~517 participants
Updated 2026-05-20 on ClinicalTrials.gov
What's tested:cell-free DNA

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Overall Survival (OS)
Measured over through study completion; an average 1 year
Lymphoma

NCT05676450

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Cancer Therapy and Research Center at The UT Health Science Center at San Antonio

    San Antonio, Texasstudy coordinator listed

    Recruiting

  • MD Anderson Cancer Center

    Houston, Texasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Chijioke Nze, MD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

Opens a ready-to-send draft in your own email app — review before sending.

  • Overall Survival (OS)through study completion; an average 1 year