Yoga Therapy for Cancer Patients Undergoing Stem Cell Transplant

This study is testing an inpatient yoga therapy program for cancer patients who are having a hematopoietic stem cell transplant (HSCT), also known as a bone marrow transplant. The goal is to create a yoga program that fits different cultures in India, Tanzania, and the United States, and to see if it's practical for patients to participate. You would attend yoga sessions, complete questionnaires about your symptoms, anxiety, depression, and quality of life, and have an exit interview. The study is looking to enroll 60 participants aged 18 or older who are scheduled for an HSCT and can speak English, Hindi, or Swahili. The main measure of success is how your health questionnaire scores change over about one year.

Study design
This is an interventional study with a planned enrollment of 60 participants. It is designed to develop and test a culturally tailored yoga therapy program.
What's involved
You would participate in up to 12 yoga sessions (3 per week) starting two weeks before your transplant and continuing for 30 days during hospitalization. You will also complete four questionnaires and a 30-45 minute exit interview.
Compensation
Not stated in the trial record.
Follow-up
Your health will be monitored through questionnaires for an average of one year after the study begins.

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NCT05681026

Cultural Tailoring and Pilot Testing of an Inpatient Yoga Therapy Program for Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation in India, Tanzania, and the United States

Recruiting
NAAges 18+InterventionalSupportive care
M.D. Anderson Cancer Center
~60 participants
Updated 2026-02-27 on ClinicalTrials.gov
What's tested:Yoga SessionsQuestionnariesInterviews

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Patient Health Questionnaire-8 (PHQ-8)
Measured over through study completion; an average of 1 year
Hematopoietic Stem Cell Transplantation
Cancer
3 sites across 3 states
Texas1
Karnataka1
Tanzania1
  • Lorenzo Cohen, PHD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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Eligibility criteria

Exclusion

Extreme mobility issues that preclude participating in the YT;
Major thought disorders such as schizophrenia or uncontrolled bipolar disorder;
HCT comorbidity score of 3 or higher, excluding cancer diagnoses
  • Patient Health Questionnaire-8 (PHQ-8)through study completion; an average of 1 year

    The PHQ-8 is a 8-item self-report questionnaire used to assess bother of depressive symptoms over the past 2 weeks. The PHQ-8 is a 8-item questionnaire to screen for degree of depressive symptoms scored on a 0-24 scale with higher scores indicating greater distress and impairment