Understanding Sleep and Alcohol Use in Young Adults

This study is looking at how sleep patterns affect risky alcohol use in young adults. Researchers are comparing two behavioral interventions: "Sleep extension and advance," where participants extend their sleep and go to bed earlier, and "Regular sleep duration and timing," where participants maintain their usual sleep schedule. The goal is to understand how sleep relates to brain functions linked to reward and stress, which can influence alcohol use. They will measure alcohol use after two months, and brain function related to reward and stress after two weeks. You might be eligible if you are 18-24 years old, engage in high-risk drinking (e.g., 4+ drinks/day or 8+/week for women; 5+ drinks/day or 15+/week for men), and have specific sleep patterns (either short and late sleep or long and early sleep). The current status of this study is unclear.

Study design
This interventional study plans to enroll 90 young adults. It compares two behavioral approaches to sleep.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Alcohol use will be measured at 2 months, and brain function related to reward and stress will be measured at 2 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05684094

Mechanisms of Risky Alcohol Use in Young Adults: Linking Sleep to Reward- and Stress-Related Brain Function

Recruiting
NAAges 18–24InterventionalBasic science
University of Oregon
~90 participants
Updated 2026-02-27 on ClinicalTrials.gov
What's tested:Sleep extension and advanceRegular sleep duration and timing

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Alcohol use
Measured over 2 months
+2 more outcomes measured
Alcohol Use Disorder
1 sites across 1 states
Oregon1
  • Melynda D Casement, PhD · PRINCIPAL_INVESTIGATOR · University of Oregon

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  • Alcohol use2 months

    The Alcohol Timeline Follow-Back (TLFB) will be administered electronically to assess the quantity (number of standard drinks) and frequency of alcohol use over the past 2 months, beginning at screening and continuing at least every 2 months through the follow-up assessment. The TLFB uses a calendar, anchor dates, and standard drink conversions to obtain retrospective estimates of alcohol use.

  • Reward-related brain function2 weeks

    Functional magnetic resonance imaging (fMRI) during the Monetary Incentive Delay task (MID, 92) will be used to measure blood oxygen level dependent (BOLD) regional response and functional connectivity related to anticipation and receipt of monetary rewards. This task reliably elicits activation in neural reward circuitry

  • Stress-related brain function2 weeks

    Stress-related brain function will be indexed using autonomic and neuroendocrine measures taken before and during the Trier Social Stress Task (TSST). The TSST is a lab-based social-evaluative threat task that reliably elicits subjective stress and increases in the stress-hormone cortisol.