Tied Tube Trial in Glaucoma Surgery
This study is looking at a surgical technique for people with glaucoma (a condition that damages the optic nerve and can lead to vision loss) who are having an Ahmed Glaucoma Valve (AGV) implanted. Researchers want to see if delaying the flow of fluid through the AGV, by using a special stitch called a vicryl ligature, can lead to better outcomes after surgery. You could be eligible if you are at least 18 years old, have glaucoma that isn't well-controlled, and are scheduled for an AGV implant. The study will measure changes in your eye pressure (IOP) at different times over 12 months to see if the new technique is more effective. The current status of this study is unclear.
- Study design
- This is an observational, randomized study involving 152 participants. Participants will be randomly assigned to receive either the standard AGV implantation or the AGV implantation with the vicryl ligature.
- What's involved
- Your eye pressure will be measured at day one, week one, and months one, three, six, and twelve after surgery. Clinical data on glaucoma medications and post-operative complications will also be collected.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 12 months after surgery, with eye pressure measurements taken at specific intervals.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Tied Tube Trial in Glaucoma Surgery
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- James Liu, MD · PRINCIPAL_INVESTIGATOR · Washington University St. Louis MO
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- IOP ChangeMonths 1, 3 , 6, and 12
Change IOP