This study is looking at how squamous cell carcinoma (SCC), a type of cancer, develops in people with Fanconi Anemia (FA), an inherited disorder. People with FA are at higher risk for SCC, especially in the mouth, esophagus, and genital areas. This observational study aims to regularly screen individuals with FA to better understand the natural history of these cancers and early signs of cancer. The study is open to people with FA aged 12 and older, and some children aged 8-11 with specific symptoms. Researchers will collect information through questionnaires, physical exams, blood and saliva samples, and by reviewing medical records. The goal is to improve early detection of SCC in people with FA.

Study design

This is an observational study planning to enroll 200 participants. It involves comprehensive screening for cancer or early signs of cancer.

What's involved

Participants will have a physical exam and provide blood and saliva samples. They will also complete questionnaires and undergo clinical and research evaluations.

Compensation

Not stated in the trial record.

Follow-up

The study measures outcomes like screening patients with FA and the natural history of oral lesions on an ongoing basis.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.