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Clinical Decision Support System for Ventilator Weaning in Children After Cardiac Surgery

This study is looking at how a special computer program, called a Clinical Decision Support System (CDSS), can help children with congenital heart disease (a heart problem present at birth) who need a breathing machine (mechanical ventilation) after surgery. The CDSS is built into a software platform (T3) that gathers information from your child's monitors and lab results. Doctors and nurses will use the CDSS to help decide when to take your child off the breathing machine. Researchers want to see if using this system can help children come off the breathing machine sooner. This study is for children under 12 years old who have had heart surgery and have been on a breathing machine for at least 48 hours at Boston Children's Hospital. The goal is to reduce the time children spend on mechanical ventilation, which will be measured up to 28 days after surgery. The current status of this study is unclear.

Study design
This is an observational study involving 330 participants. Researchers will compare patients whose care involves the CDSS with a group of past patients.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The main outcome, duration of mechanical ventilation, will be measured up to 28 days after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05687292

Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children

Recruiting
Not specifiedAges 1–12Observational
Boston Children's Hospital
~330 participants
Updated 2026-05-12 on ClinicalTrials.gov
What's tested:Clinical decision support system (CDSS) for ventilator weaning

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Duration of Mechanical Ventilation
Measured over Up to 28 days after surgery

Conditions

Congenital Heart Disease

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NCT05687292

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Boston Children's Hospital

    Boston, Massachusettsstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Daniel Hames, MD · PRINCIPAL_INVESTIGATOR · Boston Children's Hospital

Who to contact

Daniel L Hames, MD
[email protected]
6173554023
Email the study team

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Eligibility criteria

Inclusion

Children \< 12 years old
Post-cardiac surgery
Receiving mechanical ventilation for ≥ 48 hours in the Cardiac Intensive Care Unit at Boston Children's Hospital following surgery

Exclusion

Premature infants (\<37 weeks' gestation)
Weight \< 2kg
Baseline ventilator (via tracheostomy) or noninvasive positive pressure dependence

What this trial measures

  • Duration of Mechanical VentilationUp to 28 days after surgery

    Measured in days; Obtained from date/time of initial extubation minus date/time of admission from surgery, divided by 24 to give an exact determination of days