Nutrition for Precision Health, Powered by the All of Us
This study, called "Nutrition for Precision Health, Powered by the All of Us," aims to understand how different diets affect individuals. Researchers will use artificial intelligence to predict how your body responds to specific eating patterns. The study involves three different diets: Diet A (rich in fruits, vegetables, and whole grains), Diet B (higher in refined grains, processed foods, and sugary drinks), and Diet C (moderate-high in vegetables, meat, nuts, and dairy, with low grains and sugars). The main goal is to see how these diets impact your glucose (blood sugar), insulin, and triglyceride levels after a meal. You may be eligible to join if you are 18 or older and have already participated in the All of Us Research Program, including providing a DNA sample and completing certain health surveys. The study plans to enroll about 8,000 participants.
- Study design
- This interventional study has three modules, with about 8,000 participants in total. Some participants will follow three distinct diets in a crossover sequence at home, while others will follow the same diets in a supervised residential setting.
- What's involved
- Participants in the interventional modules will follow three distinct diets for 14 days each, with at least a 14-day break between diets. They will undergo assessments including clinical measures, biospecimen collection, wearable sensor monitoring, questionnaires, and a liquid meal test.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoints for glucose, insulin, and triglycerides are measured at 4 hours after a diet-specific mixed meal tolerance test.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Nutrition for Precision Health, Powered by the All of Us
At a glance
Conditions
Where it's being run
14 sites across 6 statesStudy leadership
- Marie G Gantz, PhD · PRINCIPAL_INVESTIGATOR · RTI International
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Glucose - Diet Specific mixed meal tolerance test (MMTT) Diet A4 hours
Area under the curve (AUC) for glucose measured during the diet-specific MMTT for Diet A.
- Insulin - Diet Specific mixed meal tolerance test (MMTT) Diet A4 hours
Area under the curve (AUC) for insulin measured during the diet-specific MMTT for Diet A.
- Triglycerides - Diet Specific mixed meal tolerance test (MMTT) Diet A4 hours
Area under the curve (AUC) for triglycerides measured during the diet-specific MMTT for Diet A.
- GLP-1 - Diet Specific mixed meal tolerance test (MMTT) Diet A4 hours
Area under the curve (AUC) for Glucagon-Like Peptide-1 (GLP-1) measured during the diet-specific MMTT for Diet A.
- Glucose - Diet Specific mixed meal tolerance test (MMTT) Diet B4 hours
Area under the curve (AUC) for glucose measured during the diet-specific MMTT for Diet B.
- Insulin - Diet Specific mixed meal tolerance test (MMTT) Diet B4 hours
Area under the curve (AUC) for insulin measured during the diet-specific MMTT for Diet B.
- Triglycerides - Diet Specific mixed meal tolerance test (MMTT) Diet B4 hours
Area under the curve (AUC) for triglycerides measured during the diet-specific MMTT for Diet B.
- GLP-1 - Diet Specific mixed meal tolerance test (MMTT) Diet B4 hours
Area under the curve (AUC) for Glucagon-Like Peptide-1 (GLP-1) measured during the diet-specific MMTT for Diet B.
- Glucose - Diet Specific mixed meal tolerance test (MMTT) Diet C4 hours
Area under the curve (AUC) for glucose measured during the diet-specific MMTT for Diet C.
- Insulin - Diet Specific mixed meal tolerance test (MMTT) Diet C4 hours
Area under the curve (AUC) for insulin measured during the diet-specific MMTT for Diet C.
- Triglycerides - Diet Specific mixed meal tolerance test (MMTT) Diet C4 hours
Area under the curve (AUC) for triglycerides measured during the diet-specific MMTT for Diet C.
- GLP-1 - Diet Specific mixed meal tolerance test (MMTT) Diet C4 hours
Area under the curve (AUC) for Glucagon-Like Peptide-1 (GLP-1) measured during the diet-specific MMTT for Diet C.