Imaging the Pathogenesis of Cerebral Small Vessel Disease
This observational study aims to understand how cerebral small vessel disease (CSVD) progresses. CSVD can lead to problems with thinking and memory (vascular cognitive impairment and dementia). Researchers will use special MRI scans to look at changes in the brain's white matter over time. You might be able to join if you've had an ischemic stroke, have a vascular risk factor like high blood pressure, high cholesterol, or diabetes, and show signs of CSVD on an MRI. The main goal is to see how CSVD changes over one year. This study is currently unclear about its recruitment status.
- Study design
- This is an observational study planning to enroll 50 participants. It will track changes in the brain using MRI scans.
- What's involved
- You would need to complete 3 research MRI scans over approximately 1.25 years.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint measures progression of cerebral small vessel disease at 1 year.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Imaging the Pathogenesis of Cerebral Small Vessel Disease
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Richard Leigh, MD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Progression of cerebral small vessel disease1 year
Conversion of normal appearing white matter to white matter hyperintensity measured on MRI using 3D FLAIR imaging.