NCT05704309

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

Enrolling by Invitation
Not specifiedAll AgesObservational
Marinella Temprosa
~1,976 participants
Updated 2025-08-26 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 27 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Cognitive Diagnoses
Measured over Sept 2022 to October 2026
Diabetes
Alzheimer Disease
Dementia, Vascular
Dementia
PreDiabetes
27 sites across 18 states
New Mexico3
New York3
California2
Illinois2
Maryland2
Massachusetts2
Pennsylvania2
Arizona1
  • Jose Luchsinger · PRINCIPAL_INVESTIGATOR · Columbia University
  • David Nathan · STUDY_CHAIR · Massachusetts General Hospital
  • Marinell Temprosa · PRINCIPAL_INVESTIGATOR · George Washington University

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

All surviving participants originally randomized in the Diabetes Prevention Program
For Brain Imaging subcohort, only participants aged 55 years and older and those without contraindication to MRI will be included. Contraindications to MRI include the inability to lie flat, claustrophobia, and the presence of indwelling metallic objects, medical or non-medical, that are not 3T MRI compatible.
  • Cognitive DiagnosesSept 2022 to October 2026

    Classification of normal, mild cognitive impairment or dementia based on NACC UDS