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Diet and Cognitive Training for Blood Cancer Survivors

This study is looking at whether a modified ketogenic diet, using KetoCal, combined with online cognitive (brain) training through Lumosity can help improve thinking skills in people who have survived blood cancer. You might be able to join if you are an adult (21 years or older) who has had a blood cancer and are experiencing mild to moderate cognitive impairment (problems with memory or thinking). The study aims to see if this combination of diet and training is practical and if it improves cognitive function. The main goals are to see how many people complete the program and if their cognitive function improves after 12 weeks. The current status of this study is unclear, and it plans to enroll 80 participants.

Study design
This is an interventional study with 80 planned participants. It is a randomized trial where some participants will receive the combined intervention immediately, and others will be on a waitlist before receiving the cognitive training.
What's involved
Participants will follow a modified ketogenic diet using KetoCal daily and complete 5 online cognitive training tasks daily for 12 weeks.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints are measured at 12 weeks, focusing on changes in cognitive function from baseline to 12 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05708716

Diet and Cognitive Training in Hematologic Cancer Survivors

Recruiting
Not specifiedAll Ages
Updated 2026-08-26T02:18:09.641312+00:00 on ClinicalTrials.gov

Conditions

Cognitive Impairment
Hematologic Malignancy

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Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Adult with hematologic malignancy diagnosed at age ≥21 years
Outpatient at least 3 months from completion of blood or marrow transplant (BMT) or at least 6 months from diagnosis for patients not treated with BMT
Evidence of mild-to-moderate cognitive impairment using either the Modified Telephone Interview for Mild Cognitive Impairment (TICS-M) or PROMIS 8a short form raw score = 19 -37
Have daily access to an internet-connected home computer
Can fluently read and write in English
Can understand and sign the study-specific Informed Consent Form

Exclusion

History of pre-existing neurological disorder or documented major psychiatric disorder
Significant auditory, visual, or motor impairments
History of color blindness
Participated in neuropsychological intervention within the past 6 months
Evidence of active chronic graft vs. host disease (GvHD) for allogeneic BMT
History of pre-existing metabolic disease
Allergies to soy or milk
Body Mass Index (BMI) ≤20