AMDX-2011P for Cerebral Amyloid Angiopathy (CAA)

This study is testing a drug called AMDX-2011P in people with Cerebral Amyloid Angiopathy (CAA), a condition where proteins build up in the brain's blood vessels. The main goal is to see if AMDX-2011P is safe and well-tolerated when given as a single injection. Researchers will also look at how the drug moves through the body and if it has any biological effects. You might be able to join if you are 18 or older and have a diagnosis of CAA, confirmed by genetic testing or specific brain imaging (MRI) criteria. The study aims to enroll 25 participants, but its current recruitment status is unclear.

Study design
This is an open-label study, meaning you and the study team will know you are receiving AMDX-2011P. It involves a single treatment and aims to enroll 25 participants.
What's involved
You would be admitted to the study site for an eye exam and retinal imaging before receiving a single intravenous (IV) injection of AMDX-2011P. Afterward, safety checks, more retinal imaging, and blood draws will be performed.
Compensation
Not stated in the trial record.
Follow-up
Your safety will be assessed for 8 days after receiving the AMDX-2011P injection.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT05709314

A Study of AMDX-2011P in Participants With CAA

Recruiting
PHASE2Ages 18+InterventionalDiagnostic
Amydis Inc.
~25 participants
Updated 2026-02-13 on ClinicalTrials.gov
What's tested:AMDX-2011P

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
AMDX-2011P Adverse Events Profile
Measured over 8 days
Cerebral Amyloid Angiopathy
1 sites across 1 states
Arizona1

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  • AMDX-2011P Adverse Events Profile8 days

    Incidence, nature and severity of AEs/SAEs