Study of Non-Ischemic Exercise for Peripheral Artery Disease
This study is testing a new, pain-free exercise program called Non-Ischemic Exercise (NICE) for people with Peripheral Artery Disease (PAD), a condition that causes leg pain when walking (claudication). Researchers want to see if NICE is better than the standard painful exercise program at improving how far and how long you can walk. They will also look at how it affects blood flow in your calf muscles. You might be able to join if you are 40 or older, have a history of claudication, and meet specific walking and blood pressure criteria. The study aims to enroll 100 participants.
- Study design
- This is a 3-month randomized controlled trial, meaning 100 participants will be randomly assigned to either the NICE program or the standard exercise program.
- What's involved
- You would participate in an exercise program for 3 months. Your walking time and calf muscle oxygen levels will be measured at the end of this period.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your progress will be measured at 3 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Effects of a Novel, Non-ischemic and Pain-free Exercise Intervention in Peripheral Artery Disease
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Andrew W. Gardner, Ph.D · PRINCIPAL_INVESTIGATOR · Professor, Department of Medicine, Cardiology
Who to contact
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What this trial measures
- Peak Walking Time3 months
The change in peak walking time from the pre-test value to the post-test value (seconds)
- Calf Muscle Oxygen Saturation3 months
The change in calf muscle oxygen saturation value during exercise from the pre-test value to the post-test value (% saturation)